One weekly injection of Trulicity (dulaglutide) is used to treat type 2 diabetes. It belongs to a group of medications called GLP-1 receptor agonists. These medications slow down digestion, control glucagon, and aid in the production of insulin thus Trulicity weight loss works.
Diabetes presents special health difficulties. One of them is keeping a healthy weight. Almost 90% of persons with diabetes in the United States are overweight or obese. Naturally, a lot of diabetics are curious in which diabetes drugs can aid in weight loss.
One possible solution is Trulicity (dulaglutide). When taken in conjunction with a diabetic-friendly diet and regular exercise, this FDA-approved drug treats Type 2 diabetes. 
Additionally, it is authorized to reduce the risk of heart issues in those with Type 2 diabetes and heart disease (or heart disease risk factors). Despite not being FDA-approved for weight loss explicitly, it can also aid in this area.
Here, we’ll talk about Trulicity weight loss:
Caution: It is not advised for those without Type 2 diabetes to take Trulicity. The FDA has approved several GLP-1 agonists, such as Wegovy (semaglutide) and Saxenda (liraglutide), specifically for weight loss. This also applies to Zepbound (tirzepatide), a drug that is closely linked to GLP-1 agonists. If you’re interested in using a GLP-1 agonist to lose weight, speak with a healthcare provider.
Trulicity For Losing Weight
In addition to managing type 2 diabetes, Trulicity may aid in weight loss. Neither medication is authorized just for this use. However, your doctor can prescribe them “off label”, that is, for a purpose other than the one for which the drug is approved, in order to help you lose weight.
How Much Weight Loss Does Trulicity Typically Result In?
Dulaglutide (Trulicity) alone may help you shed two to five pounds. Weight loss of 6 to 7 pounds is possible if metformin, a medication that lowers blood sugar, is used with it. Weight loss is typically greater with higher dosages of dulaglutide.
Weight loss is another side effect of Trulicity.
Side Effects of Trulicity
Although they are uncommon, Trulicity side effects can include:
- Pain in the stomach
- Stomach distress (indigestion)
- Having diarrhea
- Appetite loss
- Allergic reaction (swelling, breathing difficulties, and hives)
- Pancreatitis
Go to the emergency department immediately if you are experiencing symptoms of an allergic reaction.
When used in conjunction with diet and exercise, Trulicity helps persons with type 2 diabetes lower their blood sugar levels. Your doctor might not suggest Trulicity for weight loss alone, even though it might be prescribed off-label for that purpose. They might recommend Wegovy, another semaglutide drug that is authorized for weight control. To find out what could be best for you, consult your physician.
How Much Weight Can You Lose With Trulicity?
Trulicity is supplied in prefilled, disposable pens as a liquid solution (one dose per pen). The medication is administered subcutaneously once a week. Depending on the dosage strength, participants in Trulicity’s clinical trials lost varying amounts of weight on average.
There are four strengths for Trulicity:
- 0.75 mg/0.5 mL of liquid solution, or 0.75 mg/0.5 mL of liquid solution
- 0.5 mL of liquid solution containing 1.5 milligrams
- 0.5 mL of liquid solution containing 3 milligrams
- 0.5 mL of liquid solution containing 4.5 milligrams
The average weight loss in pounds (lb) following 36 weeks of Trulicity treatment is displayed here. For comparison, 1 kg is equal to 2.2 lb.
| Weekly dose | Weight loss at 36 weeks |
| 1.4mg | 6.6lb |
| 3mg | 8.4lb |
| 4.5mg | 10.1lb |
How does weight loss occur with Trulicity?
Dulaglutide, an agonist of the glucagon-like peptide-1 (GLP-1) receptor, is the active ingredient in Trulicity.
When you have blood sugar, dulaglutide causes certain cells in your pancreas to release insulin. By transferring the sugar into your cells, insulin helps lower blood sugar levels.
Additionally, glucagon, a hormone that normally instructs your liver to break down stored sugar and release it into your bloodstream, is blocked by Trulicity. Blocking glucagon function lowers blood sugar levels even more.
By keeping blood sugar levels at optimal ranges, your body can burn fat for energy instead of storing it. This aids with weight loss.
Food passes through your stomach more slowly when you take trulicity. This prevents a sharp rise in blood sugar levels after meals. Additionally, it prolongs feelings of fullness, which makes you eat less in general.
In addition to controlling blood sugar, Trulicity’s adverse effects may cause weight reduction. Among the frequently mentioned adverse effects of this medication include decreased appetite.
- Issues with the digestive system
- Discomfort in the abdomen
- Other minor adverse effects include nausea, vomiting, indigestion, and diarrhea.
In Conclusion
Trulicity is prescribed by a medical expert in conjunction with dietary and exercise modifications. These could assist you in achieving or keeping a healthy weight.
Consult your physician about the best course of action about Trulicity weight loss for you if you’re attempting to reduce your weight.
